USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: SRSF4_HUMAN USC-OGP 2-DE database:  SRSF4_HUMAN SRSF4_HUMAN General information about the entry View entry in simple text format Entry name SRSF4_HUMAN Primary accession number Q08170 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Serine/arginine-rich splicing factor 4; AltName: Full=Pre-mRNA-splicing factor SRP75; AltName: Full=SRP001LB; AltName: Full=Splicing factor, arginine/serine-rich 4;. Gene name Name=SRSF4 Synonyms=SFRS4, SRP75 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1095: pI=5.32; Mw=148989 Cross-references UniProtKB/Swiss-Prot Q08170; SRSF4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SRSF4_HUMAN Primary accession number Q08170 Secondary accession number(s) Q5VXP1 Q9BUA4 Q9UEB5 Sequence was last modified on  May 15, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 169) Name and origin of the protein Description RecName: Full=Serine/arginine-rich splicing factor 4; AltName: Full=Pre-mRNA-splicing factor SRP75; AltName: Full=SRP001LB; AltName: Full=Splicing factor, arginine/serine-rich 4; Gene name Name=SRSF4 Synonyms=SFRS4, SRP75 Encoded on Name=SRSF4; Synonyms=SFRS4, SRP75 Keywords Complete proteome; Direct protein sequencing; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; RNA-binding. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L14076; AAA36649.1; -; mRNA EMBL BT007415; AAP36083.1; -; mRNA EMBL AL590729; CAI14326.1; -; Genomic_DNA EMBL AL357500; CAI14326.1; JOINED; Genomic_DNA EMBL AL357500; CAH71635.1; -; Genomic_DNA EMBL AL590729; CAH71635.1; JOINED; Genomic_DNA EMBL BC002781; AAH02781.1; -; mRNA EMBL AC004236; AAC04476.1; -; Genomic_DNA CCDS CCDS333.1; -; . PIR A48133; A48133; . RefSeq NP_005617.2; NM_005626.4; . UniGene Hs.469970; -; . ProteinModelPortal Q08170; -; . SMR Q08170; -; . BioGrid 112327; 42; . IntAct Q08170; 28; . MINT MINT-1410521; -; . STRING 9606.ENSP00000362900; -; . iPTMnet Q08170; -; . PhosphoSitePlus Q08170; -; . SwissPalm Q08170; -; . BioMuta SRSF4; -; . DMDM 20981726; -; . EPD Q08170; -; . MaxQB Q08170; -; . PaxDb Q08170; -; . PeptideAtlas Q08170; -; . PRIDE Q08170; -; . DNASU 6429; -; . Ensembl ENST00000373795; ENSP00000362900; ENSG00000116350; . GeneID 6429; -; . KEGG hsa:6429; -; . UCSC uc001bro.4; human; . CTD 6429; -; . DisGeNET 6429; -; . GeneCards SRSF4; -; . H-InvDB HIX0160019; -; . HGNC HGNC:10786; SRSF4; . HPA HPA050975; -; . MIM 601940; gene; . neXtProt NX_Q08170; -; . OpenTargets ENSG00000116350; -; . PharmGKB PA35702; -; . eggNOG KOG0106; Eukaryota; . eggNOG COG0724; LUCA; . GeneTree ENSGT00700000104103; -; . HOVERGEN HBG002295; -; . InParanoid Q08170; -; . KO K12893; -; . OMA KSKDHAE; -; . OrthoDB EOG091G0R9W; -; . PhylomeDB Q08170; -; . TreeFam TF351335; -; . Reactome R-HSA-109688; Cleavage of Growing Transcript in the Termination Region; . Reactome R-HSA-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript; . Reactome R-HSA-72163; mRNA Splicing - Major Pathway; . Reactome R-HSA-72187; mRNA 3'-end processing; . ChiTaRS SRSF4; human; . GeneWiki SFRS4; -; . GenomeRNAi 6429; -; . PRO PR:Q08170; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000116350; -; . CleanEx HS_SFRS4; -; . ExpressionAtlas Q08170; baseline and differential; . Genevisible Q08170; HS; . GO GO:0016607; C:nuclear speck; IDA:HPA; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; TAS:ProtInc; . GO GO:0000166; F:nucleotide binding; IEA:InterPro; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:1990825; F:sequence-specific mRNA binding; IEA:Ensembl; . GO GO:0031124; P:mRNA 3'-end processing; TAS:Reactome; . GO GO:0006406; P:mRNA export from nucleus; TAS:Reactome; . GO GO:0006397; P:mRNA processing; TAS:ProtInc; . GO GO:0000398; P:mRNA splicing; via spliceosome; TAS:Reactome GO GO:0048025; P:negative regulation of mRNA splicing; via spliceosome; IDA:UniProtKB GO GO:0032868; P:response to insulin; IEA:Ensembl; . GO GO:0006405; P:RNA export from nucleus; TAS:Reactome; . GO GO:0008380; P:RNA splicing; TAS:ProtInc; . GO GO:0000375; P:RNA splicing; via transesterification reactions; TAS:ProtInc GO GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome; . Gene3D 3.30.70.330; -; 2; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Pfam PF00076; RRM_1; 2; . SMART SM00360; RRM; 2; . SUPFAM SSF54928; SSF54928; 1; . PROSITE PS50102; RRM; 2; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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